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A Complementary Scale of Biased Agonism for Agonists with Differing Maximal Responses
Compelling data in the literature from the recent years leave no doubt about the pluridimensional nature of G protein-coupled receptor function and the fact that some ligands can couple with different efficacies to the multiple pathways that a receptor can signal through, a phenomenon most commonly...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5684405/ https://ncbi.nlm.nih.gov/pubmed/29133887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15258-z |
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