Regulation of angiotensin II actions by enhancers and super-enhancers in vascular smooth muscle cells

Angiotensin II (AngII) promotes hypertension and atherosclerosis by activating growth-promoting and pro-inflammatory gene expression in vascular smooth muscle cells (VSMCs). Enhancers and super-enhancers (SEs) play critical roles in driving disease-associated gene expression. However, enhancers/SEs...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Das, Sadhan, Senapati, Parijat, Chen, Zhuo, Reddy, Marpadga A., Ganguly, Rituparna, Lanting, Linda, Mandi, Varun, Bansal, Anita, Leung, Amy, Zhang, Selena, Jia, Ye, Wu, Xiwei, Schones, Dustin E., Natarajan, Rama
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684340/
https://ncbi.nlm.nih.gov/pubmed/29133788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01629-7
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