New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut

E. coli releases a 33 amino acid peptide melanocortin-like peptide of E. coli (MECO-1) that is identical to the C-terminus of the E. coli elongation factor-G (EF-G) and has interesting similarities to two prominent mammalian melanocortin hormones, alpha-melanocyte-stimulating hormone (alpha-MSH) and...

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Bibliografski detalji
Izdano u:NPJ Biofilms Microbiomes
Glavni autori: Qiang, Xiaoling, Liotta, Anthony S., Shiloach, Joseph, Gutierrez, J. C., Wang, Haichao, Ochani, Mahendar, Ochani, Kanta, Yang, Huan, Rabin, Aviva, LeRoith, Derek, Lesniak, Maxine A., Böhm, Markus, Maaser, Christian, Kannengiesser, Klaus, Donowitz, Mark, Rabizadeh, Shervin, Czura, Christopher J., Tracey, Kevin J., Westlake, Mark, Zarfeshani, Aida, Mehdi, Syed F., Danoff, Ann, Ge, Xueliang, Sanyal, Suparna, Schwartz, Gary J., Roth, Jesse
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684143/
https://ncbi.nlm.nih.gov/pubmed/29152323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41522-017-0039-9
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