Crimped Nanofibrous Biomaterials Mimic Microstructure and Mechanics of Native Tissue and Alter Strain Transfer to Cells

To fully recapitulate tissue microstructure and mechanics, fiber crimping must exist within biomaterials used for tendon/ligament engineering. Existing crimped nanofibrous scaffolds produced via electrospinning are dense materials that prevent cellular infiltration into the scaffold interior. In thi...

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Pubblicato in:ACS Biomater Sci Eng
Autori principali: Szczesny, Spencer E., Driscoll, Tristan P., Tseng, Hsiao-Yun, Liu, Pang-Ching, Heo, Su-Jin, Mauck, Robert L., Chao, Pen-Hsiu G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683713/
https://ncbi.nlm.nih.gov/pubmed/29147681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.6b00646
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