A MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage

BACKGROUND: Cigarette smoking increases risk for multiple diseases. MicroRNAs (miRNAs) regulate gene expression and may play a role in smoking-induced target organ damage. We sought to describe a miRNA signature of cigarette smoking and relate it to smoking-associated clinical phenotypes, gene expre...

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Pubblicato in:Circ Cardiovasc Genet
Autori principali: Willinger, Christine M., Rong, Jian, Tanriverdi, Kahraman, Courchesne, Paul L., Huan, Tianxiao, Wasserman, Gregory A., Lin, Honghuang, Dupuis, Josée, Joehanes, Roby, Jones, Matthew R., Chen, George, Benjamin, Emelia J., O’Connor, George T., Mizgerd, Joseph P., Freedman, Jane E., Larson, Martin G., Levy, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683429/
https://ncbi.nlm.nih.gov/pubmed/29030400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.116.001678
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