Prevalence of naturally occurring NS5A resistance-associated substitutions in patients infected with hepatitis C virus subtype 1a, 1b, and 3a, co-infected or not with HIV in Brazil

BACKGROUND: Non-structural 5A protein (NS5A) resistance-associated substitutions (RASs) have been identified in patients infected with hepatitis C virus (HCV), even prior to exposure to direct-acting antiviral agents (DAAs). Selection for these variants occurs rapidly during treatment and, in some c...

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Dettagli Bibliografici
Pubblicato in:BMC Infect Dis
Autori principali: Malta, Fernanda, Gaspareto, Karine Vieira, Lisboa-Neto, Gaspar, Carrilho, Flair José, Mendes-Correa, Maria Cássia, Pinho, João Renato Rebello
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683373/
https://ncbi.nlm.nih.gov/pubmed/29132303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-017-2817-7
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