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Efficacy and safety of ustekinumab in adolescents
The biologic agent ustekinumab is a human monoclonal antibody that binds to the p40 subunit shared by interleukins (ILs) 12 and 23. The antibody is able to prevent binding of cytokines to the IL-12Rβ1 cell surface receptor and therefore may prevent IL-23 driven activation of the IL-23/Th 17 axis of...
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| Publicado no: | Pediatric Health Med Ther |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5683279/ https://ncbi.nlm.nih.gov/pubmed/29388600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PHMT.S75836 |
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