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Demethylzeylasteral inhibits cell proliferation and induces apoptosis through suppressing MCL1 in melanoma cells

Demethylzeylasteral is one of the extracts of Tripterygium wilfordii Hook F, which plays important roles in multiple biological processes such as inflammation inhibition, as well as immunosuppression. However, anti-cancer function and the underlying mechanisms of demethylzeylasteral in melanoma cell...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Zhao, Yuzu, He, Jiang, Li, Jun, Peng, Xingzhi, Wang, Xianxing, Dong, Zhen, Zhao, Erhu, Liu, Yaling, Wu, Zonghui, Cui, Hongjuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682691/
https://ncbi.nlm.nih.gov/pubmed/29072681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.529
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