Differential regulation of spermatogenic process by Lkb1 isoforms in mouse testis

Liver serine/threonine kinase B1 (LKB1) is a tumor suppressor associated with the pathogenesis of Peutz-Jeghers syndrome. Affected males are at increased risk of developing Sertoli cell tumors and display defective spermatogenesis. Male mice lacking the short isoform (Lkb1(S)) of Lkb1 were sterile a...

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Publicado en:Cell Death Dis
Main Authors: Kong, Feifei, Wang, Mei, Huang, Xiaojing, Yue, Qiuling, Wei, Xiang, Dou, Xiaowei, Peng, Xiaoxu, Jia, Yuanyuan, Zheng, Ke, Wu, Tinghe, Yan, Jun, Li, Jing
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682689/
https://ncbi.nlm.nih.gov/pubmed/29022902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.527
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