Wild-type and mutant p53 differentially modulate miR-124/iASPP feedback following pohotodynamic therapy in human colon cancer cell line

Colorectal cancer (CRC) is a most common digestive system malignant tumor. p53 mutation has essential role in cancers and is frequently observed in CRC and presents a huge challenge. p53 mutation has been reported to attenuate the inhibitory effect of photofrin-based photodynamic therapy (PDT). p53...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Liu, Kuijie, Chen, Weidong, Lei, Sanlin, Xiong, Li, Zhao, Hua, Liang, Dong, Lei, Zhendong, Zhou, Nanjiang, Yao, Hongliang, Liang, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682646/
https://ncbi.nlm.nih.gov/pubmed/29022915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.477
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