Altered activation and connectivity in a hippocampal–basal ganglia–midbrain circuit during salience processing in subjects at ultra high risk for psychosis

Animal models of psychosis propose that abnormal hippocampal activity drives increased subcortical dopamine function, which is thought to contribute to aberrant salience processing and psychotic symptoms. These effects appear to be mediated through connections between the hippocampus, ventral striat...

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Detalles Bibliográficos
Publicado en:Transl Psychiatry
Autores principales: Winton-Brown, T, Schmidt, A, Roiser, J P, Howes, O D, Egerton, A, Fusar-Poli, P, Bunzeck, N, Grace, A A, Duzel, E, Kapur, S, McGuire, P
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682600/
https://ncbi.nlm.nih.gov/pubmed/28972591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2017.174
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