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Synthesis and Evaluation of [(18)F]RAGER: A First Generation Small-Molecule PET Radioligand Targeting the Receptor for Advanced Glycation Endproducts
The receptor for advanced glycation endproducts (RAGE) is a 35kDa transmembrane receptor that belongs to the immunoglobulin superfamily of cell surface molecules. Its role in Alzheimer’s disease (AD) is complex, but it is thought to mediate influx of circulating amyloid-β into the brain as well as a...
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| Vydáno v: | ACS Chem Neurosci |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5682588/ https://ncbi.nlm.nih.gov/pubmed/26771209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00319 |
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