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The Inactivation of ERK1/2, p38 and NF-kB Is Involved in the Down-Regulation of Osteoclastogenesis and Function by A2B Adenosine Receptor Stimulation

A2B adenosine receptor (A2BAR) is known to be the regulator of bone homeostasis, but its regulatory mechanisms in osteoclast formation are less well-defined. Here, we demonstrate the effect of A2BAR stimulation on osteoclast differentiation and activity by RANKL. A2BAR was expressed in bone marrow-d...

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Vydáno v:Mol Cells
Hlavní autoři: Kim, Bo Hyun, Oh, Ju Hee, Lee, Na Kyung
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Molecular and Cellular Biology 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682252/
https://ncbi.nlm.nih.gov/pubmed/29047264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2017.0098
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