Dynamic changes of depolarizing GABA in a computational model of epileptogenic brain: Insight for Dravet syndrome

Abnormal reemergence of depolarizing GABA(A) current during postnatal brain maturation may play a major role in paediatric epilepsies, Dravet syndrome (DS) being among the most severe. To study the impact of depolarizing GABA onto distinct patterns of EEG activity, we extended a neural mass model as...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Exp Neurol
Prif Awduron: Kurbatova, Polina, Wendling, Fabrice, Kaminska, Anna, Rosati, Anna, Nabbout, Rima, Guerrini, Renzo, Dulac, Olivier, Pons, Gérard, Cornu, Catherine, Nony, Patrice, Chiron, Catherine, Benquet, Pascal
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Academic Press 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681703/
https://ncbi.nlm.nih.gov/pubmed/27246997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.05.037
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