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Prediction of human prenatal exposure to bisphenol A and bisphenol A glucuronide from an ovine semi-physiological toxicokinetic model

Bisphenol A (BPA) risk assessment is hampered by the difficulty of determining the extent of internal exposure in the human fetus and uncertainties regarding BPA toxicokinetics (TK) in the maternal-fetal unit. A feto-maternal TK model describing BPA and BPA glucuronide (BPAG) disposition in sheep wa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gauderat, Glenn, Picard-Hagen, Nicole, Toutain, Pierre-Louis, Servien, Rémi, Viguié, Catherine, Puel, Sylvie, Lacroix, Marlène Z., Corbel, Tanguy, Bousquet-Melou, Alain, Gayrard, Véronique
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681680/
https://ncbi.nlm.nih.gov/pubmed/29127374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15646-5
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