sPAGM: inferring subpathway activity by integrating gene and miRNA expression-robust functional signature identification for melanoma prognoses

MicroRNAs (miRNAs) regulate biological pathways by inhibiting gene expression. However, most current analytical methods fail to consider miRNAs, when inferring functional or pathway activities. In this study, we developed a model called sPAGM to infer subpathway activities by integrating gene and mi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Chun-Long, Xu, Yan-Jun, Yang, Hai-Xiu, Xu, Ying-Qi, Shang, De-Si, Wu, Tan, Zhang, Yun-Peng, Li, Xia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681640/
https://ncbi.nlm.nih.gov/pubmed/29127397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15631-y
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