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Lactate Promotes Synthetic Phenotype in Vascular Smooth Muscle Cells

RATIONALE: The phenotypes of vascular smooth-muscle cells (vSMCs) comprise a continuum bounded by predominantly contractile and synthetic cells. Some evidence suggests that contractile vSMCs can assume a more synthetic phenotype in response to ischemic injury, but the mechanisms that activate this p...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Yang, Libang, Gao, Ling, Nickel, Thomas, Yang, Jing, Zhou, Jingyi, Gilbertsen, Adam, Geng, Zhaohui, Johnson, Caitlin, Young, Bernice, Henke, Craig, Gourley, Glenn R., Zhang, Jianyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681426/
https://ncbi.nlm.nih.gov/pubmed/29021296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.311819
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