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Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but not GABAergic, neurons is required for regulation of energy metabolism

OBJECTIVE: Bombesin-like receptor 3 (BRS-3) is an orphan G protein-coupled receptor. Brs3 null mice have reduced resting metabolic rate and body temperature, increased food intake, and obesity. Here we study the role of Brs3 in different neuron types. METHODS: Mice able to undergo Cre recombinase-de...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Xiao, Cuiying, Piñol, Ramón A., Carlin, Jesse Lea, Li, Cuiling, Deng, Chuxia, Gavrilova, Oksana, Reitman, Marc L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681273/
https://ncbi.nlm.nih.gov/pubmed/29107299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.08.013
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