DNA methylation of Th2 lineage determination genes at birth is associated with allergic outcomes in childhood

BACKGROUND: There is now increasing evidence that asthma and atopy originate in part in utero, with disease risk being associated with the altered epigenetic regulation of genes. OBJECTIVE AND METHODS: To determine the relationship between variations in DNA methylation at birth and the development o...

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Publicado no:Clin Exp Allergy
Main Authors: Barton, Sheila, Ngo, Sherry, Costello, Paula, Garratt, Emma, El-Heis, Sarah, Antoun, Elie, Clarke-Harris, Rebecca, Murray, Robert, Bhatt, Tejal, Burdge, Graham, Cooper, Cyrus, Inskip, Hazel, van der Beek, Eline M., Sheppard, Allan, Godfrey, Keith M., Lillycrop, Karen A
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681244/
https://ncbi.nlm.nih.gov/pubmed/28756630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12988
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