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The role of clofarabine in acute myeloid leukemia
Clofarabine is a second-generation purine nucleoside analog that has been synthesized to overcome the limitations and incorporate the best qualities of fludarabine and cladribine. Clofarabine acts by inhibiting ribonucleotide reductase and DNA polymerase, thereby depleting the amount of intracellula...
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| Publicado no: | Leuk Lymphoma |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5681218/ https://ncbi.nlm.nih.gov/pubmed/22957815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2012.726722 |
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