Hypoxic Culture Promotes Dopaminergic-Neuronal Differentiation of Nasal Olfactory Mucosa Mesenchymal Stem Cells via Upregulation of Hypoxia-Inducible Factor-1α

Olfactory mucosa mesenchymal stem cells (OM-MSCs) display significant clonogenic activity and may be easily propagated for Parkinson’s disease therapies. Methods of inducing OM-MSCs to differentiate into dopaminergic (DAergic) neurons using olfactory ensheathing cells (OECs) are thus an attractive t...

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Publicat a:Cell Transplant
Autors principals: Zhuo, Yi, Wang, Lei, Ge, Lite, Li, Xuan, Duan, Da, Teng, Xiaohua, Jiang, Miao, Liu, Kai, Yuan, Ting, Wu, Pei, Wang, Hao, Deng, Yujia, Xie, Huali, Chen, Ping, Xia, Ying, Lu, Ming
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2017
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680974/
https://ncbi.nlm.nih.gov/pubmed/28901191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0963689717720291
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