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SIRT1 and FOXO1 mRNA expression in PBMC correlates to physical activity in COPD patients

BACKGROUND: Physical activity (PA) is considered as one of the most important prognostic predictors in chronic obstructive pulmonary disease (COPD) patients. Longevity gene, SIRT1, is reported to be involved in the pathogenesis of COPD by regulating the signaling pathways of oxidative stress, inflam...

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Dettagli Bibliografici
Pubblicato in:Int J Chron Obstruct Pulmon Dis
Autori principali: Taka, Chihiro, Hayashi, Ryuji, Shimokawa, Kazuki, Tokui, Kotaro, Okazawa, Seisuke, Kambara, Kenta, Inomata, Minehiko, Yamada, Toru, Matsui, Shoko, Tobe, Kazuyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680968/
https://ncbi.nlm.nih.gov/pubmed/29138552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S144969
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