BCL6 attenuates renal inflammation via negative regulation of NLRP3 transcription

Renal inflammation contributes to the pathogeneses of hypertension. This study was designed to determine whether B-cell lymphoma 6 (BCL6) attenuates renal NLRP3 inflammasome activation and inflammation and its underlying mechanism. Male spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WK...

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Detalles Bibliográficos
Publicado en:Cell Death Dis
Main Authors: Chen, Dan, Xiong, Xiao-Qing, Zang, Ying-Hao, Tong, Ying, Zhou, Bing, Chen, Qi, Li, Yue-Hua, Gao, Xing-Ya, Kang, Yu-Ming, Zhu, Guo-Qing
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680929/
https://ncbi.nlm.nih.gov/pubmed/29072703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.567
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