Specific detection of soluble EphA2 fragments in blood as a new biomarker for pancreatic cancer

Because membrane type 1-matrix metalloproteinase 1 (MT1-MMP) and erythropoietin-producing hepatocellular receptor 2 (EphA2) expression are upregulated by the Ras/mitogen-activated protein kinase pathway, they are frequently coexpressed in malignant tumors. MT1-MMP cleaves the N-terminal ligand-bindi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Koshikawa, Naohiko, Minegishi, Tomoko, Kiyokawa, Hirofumi, Seiki, Motoharu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680914/
https://ncbi.nlm.nih.gov/pubmed/29072678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.545
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