Generation of murine macrophage-derived cell lines expressing porcine CD163 that support porcine reproductive and respiratory syndrome virus infection

BACKGROUND: Porcine reproductive and respiratory syndrome virus (PRRSV) exhibits a highly restricted tropism for cells of the monocyte-macrophage lineage, utilizing porcine CD163 (pCD163) as an indispensable cellular receptor for infection. Transfection the gene of pCD163 into several non-permissive...

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Detalhes bibliográficos
Publicado no:BMC Biotechnol
Main Authors: Li, Liangliang, Wu, Chunyan, Hou, Gaopeng, Xue, Biyun, Xie, Sha, Zhao, Qin, Nan, Yuchen, Zhang, Gaiping, Zhou, En-Min
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680797/
https://ncbi.nlm.nih.gov/pubmed/29121904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-017-0399-5
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