The level of caveolin-1 expression determines response to TGF-β as a tumour suppressor in hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is a heterogeneous tumour associated with poor prognostic outcome. Caveolin-1 (CAV1), a membrane protein involved in the formation of caveolae, is frequently overexpressed in HCC. Transforming growth factor-beta (TGF-β) is a pleiotropic cytokine having a dual role in h...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Moreno-Càceres, Joaquim, Caballero-Díaz, Daniel, Chike Nwosu, Zeribe, Meyer, Christoph, López-Luque, Judit, Malfettone, Andrea, Lastra, Raquel, Serrano, Teresa, Ramos, Emilio, Dooley, Steven, Fabregat, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680590/
https://ncbi.nlm.nih.gov/pubmed/29022911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.469
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