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Prenatal maternal plasma DNA screening for cystic fibrosis: A computer modelling study of screening performance

Background: Prenatal cystic fibrosis (CF) screening is currently based on determining the carrier status of both parents. We propose a new method based only on the analysis of DNA in maternal plasma. Methods: The method relies on the quantitative amplification of the CF gene to determine the percent...

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Veröffentlicht in:F1000Res
Hauptverfasser: Old, Robert W., Bestwick, Jonathan P., Wald, Nicholas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: F1000 Research Limited 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680537/
https://ncbi.nlm.nih.gov/pubmed/29167740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.12849.1
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