A Microdevice Platform Recapitulating Hypoxic Tumor Microenvironments

Hypoxia plays a central role in cancer progression and resistance to therapy. We have engineered a microdevice platform to recapitulate the intratumor oxygen gradients that drive the heterogeneous hypoxic landscapes in solid tumors. Our design features a “tumor section”-like culture by incorporating...

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Udgivet i:Sci Rep
Main Authors: Ando, Yuta, Ta, Hoang P., Yen, Daniel P., Lee, Sang-Sin, Raola, Sneha, Shen, Keyue
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680268/
https://ncbi.nlm.nih.gov/pubmed/29123197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15583-3
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