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Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis

The plasma membrane is uniquely enriched in phosphatidylserine (PtdSer). This anionic phospholipid is restricted almost exclusively to the inner leaflet of the plasmalemma. Because of their high density, the headgroups of anionic lipids experience electrostatic repulsion that, being exerted asymmetr...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Hirama, Takashi, Lu, Stella M., Kay, Jason G., Maekawa, Masashi, Kozlov, Michael M., Grinstein, Sergio, Fairn, Gregory D.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680216/
https://ncbi.nlm.nih.gov/pubmed/29123120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01554-9
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