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Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling

Artemether-lumefantrine (AL) is the most widely-recommended treatment for uncomplicated Plasmodium falciparum malaria worldwide. Its safety and efficacy have been extensively demonstrated in clinical trials; however, its performance in routine health care settings, where adherence to drug treatment...

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Pubblicato in:Nat Commun
Autori principali: Challenger, Joseph D., Bruxvoort, Katia, Ghani, Azra C., Okell, Lucy C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680187/
https://ncbi.nlm.nih.gov/pubmed/29123086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01352-3
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