Cerebrospinal Fluid NLRP3 is Increased after Severe Traumatic Brain Injury in Infants and Children

BACKGROUND: Inflammasome-mediated neuroinflammation may cause secondary injury following traumatic brain injury (TBI) in children. The pattern recognition receptors NLRP1 and NLRP3 are essential components of their respective inflammasome complexes. We sought to investigate whether NLRP1 and/or NLRP...

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Pubblicato in:Neurocrit Care
Autori principali: Wallisch, Jessica S., Simon, Dennis W., Bayır, Hülya, Bell, Michael J., Kochanek, Patrick M., Clark, Robert S. B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680164/
https://ncbi.nlm.nih.gov/pubmed/28181102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12028-017-0378-7
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