Cerebrospinal Fluid NLRP3 is Increased after Severe Traumatic Brain Injury in Infants and Children

BACKGROUND: Inflammasome-mediated neuroinflammation may cause secondary injury following traumatic brain injury (TBI) in children. The pattern recognition receptors NLRP1 and NLRP3 are essential components of their respective inflammasome complexes. We sought to investigate whether NLRP1 and/or NLRP...

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Publicat a:Neurocrit Care
Autors principals: Wallisch, Jessica S., Simon, Dennis W., Bayır, Hülya, Bell, Michael J., Kochanek, Patrick M., Clark, Robert S. B.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680164/
https://ncbi.nlm.nih.gov/pubmed/28181102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12028-017-0378-7
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