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Autologous tolerogenic dendritic cells derived from monocytes of systemic lupus erythematosus patients and healthy donors show a stable and immunosuppressive phenotype

Systemic lupus erythematosus (SLE) is an autoimmune disease with unrestrained T‐cell and B‐cell activity towards self‐antigens. Evidence shows that apoptotic cells (ApoCells) trigger an autoreactive response against nuclear antigens in susceptible individuals. In this study, we focus on generating a...

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Bibliographic Details
Published in:Immunology
Main Authors: Obreque, Javiera, Vega, Fabián, Torres, Andy, Cuitino, Loreto, Mackern‐Oberti, Juan P., Viviani, Paola, Kalergis, Alexis, Llanos, Carolina
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680052/
https://ncbi.nlm.nih.gov/pubmed/28763099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12806
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