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Model-based local density sharpening of cryo-EM maps

Atomic models based on high-resolution density maps are the ultimate result of the cryo-EM structure determination process. Here, we introduce a general procedure for local sharpening of cryo-EM density maps based on prior knowledge of an atomic reference structure. The procedure optimizes contrast...

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Pubblicato in:eLife
Autori principali: Jakobi, Arjen J, Wilmanns, Matthias, Sachse, Carsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679758/
https://ncbi.nlm.nih.gov/pubmed/29058676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27131
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