Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis

Adoptive cellular therapy (ACT) with the Th17 subset of CD4(+) T cells can cure established melanoma in preclinical models and holds promise for treating human cancer. However, little is known about the growth factors necessary for optimal engraftment and anti-tumor activity of Th17 cells. Due to th...

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Bibliografiske detaljer
Udgivet i:Cancer Immunol Immunother
Main Authors: Neitzke, Daniel J., Bowers, Jacob S., Andrijauskaite, Kristina, O’Connell, Nathaniel S., Garrett-Mayer, Elizabeth, Wrangle, John, Li, Zihai, Paulos, Chrystal M., Cole, David J., Rubinstein, Mark P.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679708/
https://ncbi.nlm.nih.gov/pubmed/28280853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-017-1965-3
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