Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice

BACKGROUND: Cardiac rupture is an important cause of death in the acute phase after myocardial infarction (MI). Macrophages play a pivotal role in cardiac remodeling after MI. Apoptosis inhibitor of macrophage (AIM) is secreted specifically by macrophages and contributes to macrophage accumulation i...

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Vydáno v:PLoS One
Hlavní autoři: Ishikawa, Shohei, Noma, Takahisa, Fu, Hai Ying, Matsuzaki, Takashi, Ishizawa, Makoto, Ishikawa, Kaori, Murakami, Kazushi, Nishimoto, Naoki, Nishiyama, Akira, Minamino, Tetsuo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679665/
https://ncbi.nlm.nih.gov/pubmed/29121663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187894
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