KSHV inhibits stress granule formation by viral ORF57 blocking PKR activation

TIA-1 positive stress granules (SG) represent the storage sites of stalled mRNAs and are often associated with the cellular antiviral response. In this report, we provide evidence that Kaposi’s sarcoma-associated herpesvirus (KSHV) overcomes the host antiviral response by inhibition of SG formation...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Sharma, Nishi R., Majerciak, Vladimir, Kruhlak, Michael J., Zheng, Zhi-Ming
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679657/
https://ncbi.nlm.nih.gov/pubmed/29084250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006677
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