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A method to quantify mechanobiologic forces during zebrafish cardiac development using 4-D light sheet imaging and computational modeling

Blood flow and mechanical forces in the ventricle are implicated in cardiac development and trabeculation. However, the mechanisms of mechanotransduction remain elusive. This is due in part to the challenges associated with accurately quantifying mechanical forces in the developing heart. We present...

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Опубликовано в: :PLoS Comput Biol
Главные авторы: Vedula, Vijay, Lee, Juhyun, Xu, Hao, Kuo, C.-C. Jay, Hsiai, Tzung K., Marsden, Alison L.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679653/
https://ncbi.nlm.nih.gov/pubmed/29084212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005828
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