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Haplotype CGC from XPD, hOGG1 and ITGA2 polymorphisms increases the risk of nasopharyngeal carcinoma in Malaysia

BACKGROUND: 8-oxoG, a common DNA lesion resulting from reactive oxygen species (ROS), has been shown to be associated with cancer initiation. hOGG1 DNA glycosylase is the primary enzyme responsible for excision of 8-oxoG through base excision repair (BER). Integrins are members of a family of cell s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ban, Eng-Zhuan, Lye, Munn-Sann, Chong, Pei Pei, Yap, Yoke-Yeow, Lim, Siew Ying Crystale, Abdul Rahman, Hejar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679532/
https://ncbi.nlm.nih.gov/pubmed/29121049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187200
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