Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer

BACKGROUND: Pancreatic cancer, one of the top two most fatal cancers, is characterized by a desmoplastic reaction that creates a dense microenvironment, promoting hypoxia and inducing the epithelial-to-mesenchymal transition (EMT) to facilitate invasion and metastasis. Recent evidence indicates that...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cancer
Main Authors: Li, Hongzhe, Wang, Xinjing, Wen, Chenlei, Huo, Zhen, Wang, Weishen, Zhan, Qian, Cheng, Dongfeng, Chen, Hao, Deng, Xiaxing, Peng, Chenghong, Shen, Baiyong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679488/
https://ncbi.nlm.nih.gov/pubmed/29121972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0738-0
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