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An unfolding story: Small molecules remedy misfolded monoamine transporters

The key role of monoamine transporters is to take up neurotransmitters from the synaptic cleft and rapidly terminate neurotransmission. Monoamine transporters begin their journey by folding in the endoplasmic reticulum. Upon achieving their natively-folded state, the oligomerized transporters engage...

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Détails bibliographiques
Publié dans:Int J Biochem Cell Biol
Auteurs principaux: Kasture, Ameya, Stockner, Thomas, Freissmuth, Michael, Sucic, Sonja
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679356/
https://ncbi.nlm.nih.gov/pubmed/28890376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2017.09.004
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