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TNF-R1 and FADD mediate UVB-Induced activation of K(+) channels in corneal epithelial cells

The goal of this study was to elucidate the role of Fas, TNF-R1, FADD and cytochrome c in UVB-induced K(+) channel activation, an early step in UVB-induced apoptosis, in human corneal limbal epithelial (HCLE) cells. HCLE cells were treated with Fas, TNF-R1 or FADD siRNA and exposed to 80 or 150 mJ/c...

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Vydáno v:Exp Eye Res
Hlavní autoři: Boersma, Peter M., Haarsma, Loren D., Schotanus, Mark P., Ubels, John L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679195/
https://ncbi.nlm.nih.gov/pubmed/27818316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2016.11.003
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