Association of Natural Killer Cell Ligand Polymorphism, HLA-C Asn80Lys, with the Development of Anti-SSA/Ro Associated Congenital Heart Block

OBJECTIVE: Fetal exposure to maternal anti-SSA/Ro antibodies is necessary but insufficient for the development of autoimmune congenital heart block (CHB), suggesting that other factors, such as fetal genetic predisposition, are important. Given the prior MHC and CHB risk association, here we test th...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Ainsworth, Hannah C., Marion, Miranda C., Brucato, Antonio, Costedoat-Chalumeau, Nathalie, Bertero, Tiziana, Cimaz, Rolando, Fredi, Micaela, Gaffney, Pat, Kelly, Jennifer, Levesque, Kateri, Maltret, Alice, Morel, Nathalie, Ramoni, Veronique, Ruffatti, Amelia, Langefeld, Carl D., Buyon, Jill P., Clancy, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679096/
https://ncbi.nlm.nih.gov/pubmed/29045069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40228
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