Selective Deletion of Renin-b in the Brain Alters Drinking and Metabolism

The brain specific isoform of renin (Ren-b), has been proposed as a negative regulator of the brain renin-angiotensin system (RAS). We analyzed mice with a selective deletion of Ren-b which preserved expression of the classical renin (Ren-a) isoform. We reported that Ren-b(Null) mice exhibited centr...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Shinohara, Keisuke, Nakagawa, Pablo, Gomez, Javier, Morgan, Donald A., Littlejohn, Nicole K., Folchert, Matthew D., Weidemann, Benjamin J., Liu, Xuebo, Walsh, Susan A., Ponto, Laura L., Rahmouni, Kamal, Grobe, Justin L., Sigmund, Curt D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679092/
https://ncbi.nlm.nih.gov/pubmed/28874461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09923
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