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The Impact of Non-Vitamin K Antagonist Oral Anticoagulants (NOACs) from a Basic Science Perspective
1. Inhibiting a single protease is much less “effective” at inhibiting coagulation than is inhibiting at multiple steps. Thus, the dose-response relationship between NOAC level and intensity of anti-coagulation is shallower and more linear than that of vitamin K antagonists. This partially accounts...
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| Vydáno v: | Arterioscler Thromb Vasc Biol |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5678960/ https://ncbi.nlm.nih.gov/pubmed/28798139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.306995 |
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