Development of a plasmid-based expression system in Clostridium thermocellum and its use to screen heterologous expression of bifunctional alcohol dehydrogenases (adhEs)

Clostridium thermocellum is a promising candidate for ethanol production from cellulosic biomass, but requires metabolic engineering to improve ethanol yield. A key gene in the ethanol production pathway is the bifunctional aldehyde and alcohol dehydrogenase, adhE. To explore the effects of overexpr...

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Vydáno v:Metab Eng Commun
Hlavní autoři: Hon, Shuen, Lanahan, Anthony A., Tian, Liang, Giannone, Richard J., Hettich, Robert L., Olson, Daniel G., Lynd, Lee R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678826/
https://ncbi.nlm.nih.gov/pubmed/29142822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meteno.2016.04.001
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