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Efficacy and Safety of Sparsentan Compared With Irbesartan in Patients With Primary Focal Segmental Glomerulosclerosis: Randomized, Controlled Trial Design (DUET)

INTRODUCTION: Primary focal segmental glomerulosclerosis (FSGS) is a leading cause of nephrotic syndrome and end-stage renal disease. There are no US Food and Drug Administration−approved therapies for FSGS, and treatment often fails to reduce proteinuria. Endothelin is an important factor in the pa...

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Detalhes bibliográficos
Publicado no:Kidney Int Rep
Main Authors: Komers, Radko, Gipson, Debbie S., Nelson, Peter, Adler, Sharon, Srivastava, Tarak, Derebail, Vimal K., Meyers, Kevin E., Pergola, Pablo, MacNally, Meghan E., Hunt, Jennifer L., Shih, Alvin, Trachtman, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678638/
https://ncbi.nlm.nih.gov/pubmed/29142983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ekir.2017.02.019
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