GMP-production of purified human B lymphocytes for the adoptive transfer in patients after allogeneic hematopoietic stem cell transplantation

BACKGROUND: We have recently shown that memory B cells from murine CMV immune donor animals adoptively transferred into immunodeficient mice were highly effective in protecting from a viral infection indicating a therapeutic potential of virus specific memory B cells. These preclinical data provided...

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Vydáno v:J Transl Med
Hlavní autoři: Tittlbach, Hannes, Schneider, Andrea, Strobel, Julian, Zimmermann, Robert, Maas, Stefanie, Gebhardt, Bernd, Rauser, Georg, Mach, Michael, Mackensen, Andreas, Winkler, Thomas H., Winkler, Julia
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Methodology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678567/
https://ncbi.nlm.nih.gov/pubmed/29115976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1330-5
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