DNA Vaccines Encoding Toxoplasma gondii Cathepsin C 1 Induce Protection against Toxoplasmosis in Mice

Toxoplasma gondii cathepsin C proteases (TgCPC1, 2, and 3) are important for the growth and survival of T. gondii. In the present study, B-cell and T-cell epitopes of TgCPC1 were predicted using DNAstar and the Immune Epitope Database. A TgCPC1 DNA vaccine was constructed, and its ability to induce...

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Publicado en:Korean J Parasitol
Autores principales: Han, Yali, Zhou, Aihua, Lu, Gang, Zhao, Guanghui, Sha, Wenchao, Wang, Lin, Guo, Jingjing, Zhou, Jian, Zhou, Huaiyu, Cong, Hua, He, Shenyi
Formato: Artigo
Lenguaje:Inglês
Publicado: The Korean Society for Parasitology and Tropical Medicine 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678475/
https://ncbi.nlm.nih.gov/pubmed/29103265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3347/kjp.2017.55.5.505
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