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Impaired development of the cerebral cortex in infants with congenital heart disease is correlated to reduced cerebral oxygen delivery

Neurodevelopmental impairment is the most common comorbidity associated with complex congenital heart disease (CHD), while the underlying biological mechanism remains unclear. We hypothesised that impaired cerebral oxygen delivery in infants with CHD is a cause of impaired cortical development, and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kelly, Christopher J., Makropoulos, Antonios, Cordero-Grande, Lucilio, Hutter, Jana, Price, Anthony, Hughes, Emer, Murgasova, Maria, Teixeira, Rui Pedro A. G., Steinweg, Johannes K., Kulkarni, Sagar, Rahman, Loay, Zhang, Hui, Alexander, Daniel C., Pushparajah, Kuberan, Rueckert, Daniel, Hajnal, Joseph V., Simpson, John, Edwards, A. David, Rutherford, Mary A., Counsell, Serena J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678433/
https://ncbi.nlm.nih.gov/pubmed/29118365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14939-z
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