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Inter-individual variation in genes governing human hippocampal progenitor differentiation in vitro is associated with hippocampal volume in adulthood

Hippocampal volumes are smaller in psychiatric disorder patients and lower levels of hippocampal neurogenesis are the hypothesized cause. Understanding which molecular processes regulate hippocampal progenitor differentiation might aid in the identification of novel drug targets that can promote lar...

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發表在:Sci Rep
Main Authors: Powell, Timothy R., Murphy, Tytus, Lee, Sang H., Duarte, Rodrigo R. R., Lee, Hyun Ah, Smeeth, Demelza, Price, Jack, Breen, Gerome, Thuret, Sandrine
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678432/
https://ncbi.nlm.nih.gov/pubmed/29118430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15042-z
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